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. 2013 Aug 13;8(8):e70964. doi: 10.1371/journal.pone.0070964

Table 2. meta analysis of the two SNPs detected in the first-set screening analysis.

P value of original study current study (screeing+replication) current study+PGC BP current study+Lee et al. current study+Lee et al.+PGC BP
Chr SNP GENE A1a A2b PGC BP Lee et al.c phenotyped P ORe I2 P ORe I2 P ORe I2 P ORe I2
3 rs2251219 PBRM1 A G 5.5E-07 - BD 0.0048 1.13 0 9.4E-09 1.13 0
SCZ 0.00016 1.15 0 4.3E-10 1.13 0
Psychosis 8.0E-05 1.14 0 2.0E-10 1.13 0
7 rs2709722 SP8 T C 0.089 5.06E-05 BD 0.0016 0.86 0 0.0322 0.91 56.2 5.1E-07 0.84 0 0.0070 0.88 72.9
SCZ 0.0030 0.89 46.6 0.0332 0.92 58.4 1.6E-06 0.86 42.2 0.0074 0.89 73.9
Psychosis 0.00040 0.88 32.4 0.0212 0.91 64.6 2.1E-07 0.86 30.3 0.0043 0.89 74.7

a: A1: first allele code.

b: A2: second allele code.

c: Lee et al. reported the P values based upon dominant model. To conduct meta-analysis of allelic model, we re-caluculated P values based upon their results.

d: BD: bipolar disorder, SCZ: schizophrenia.

e: the effect is with respect to the A1 allele.