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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Curr Opin Chem Biol. 2013 May 24;17(4):672–681. doi: 10.1016/j.cbpa.2013.04.026

Figure 1.

Figure 1

Fluorescent probes for labeling and imaging secretory vesicles. FM1-43 is fluorescent in the membrane but nonfluorescent in the solution. pHluorin and FFN102 are weakly fluorescent in the lumen of secretory vesicles (pH < 6), but emit much stronger fluorescence during exocytosis when they are exposed to the extracellular medium (pH 7.3).