Figure 1.

The averaged post-contrast MR images (top row), the difference images between pre- and post-contrast DCE data (middle row), and K^trans values superimposed on the averaged post-contrast images (bottom row) at three time points (three columns) for one pathological complete responder. The mean values of K^trans at three time points estimated by TK are 0.21 min⁻¹, 0.19 min⁻¹, and 0 min⁻¹, respectively, using a 80% enhancement threshold.