Figure 2. Medea^dah and Medea^o-fut1 drive population replacement.

Fraction of the adult population that is transgenic is plotted versus number of generations for both Medea^dah (thin blue lines) and Medea^o-fut1 (thin green lines). Expected transgenic frequencies for a Medea with no fitness cost (s = 0) are indicated by the black line. Predicted behavior of Medea elements with fitness costs corresponding to best-fit estimates Medea^dah (bold blue line) and Medea^o-fut1 (bold green line) were derived from actual Medea^dah and Medea^o-fut1 behavior. 95% confidence intervals are indicated by light green and blue shading. s = additive fitness cost in Medea homozygotes.