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. Author manuscript; available in PMC: 2015 Dec 19.
Published in final edited form as: ACS Synth Biol. 2012 Dec 28;3(12):915–928. doi: 10.1021/sb300079h

Figure 5. Modeling the ability of Medea elements carrying genes that cause cue-dependent female lethality to bring about population eradication.

Figure 5

4,000 males homozygous for a Medea carrying a transgene cassette that induces diapause-dependent female killing are released into a total wild population of 10,000. The fate of the total population (red line), transgenics (blue line), and females (green line) are followed for 30 generations. Diapause occurs in generation 13 and generation 26 (A). 6,000 transgenic males are released into the wild population as above (B).