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. Author manuscript; available in PMC: 2015 Dec 19.
Published in final edited form as: ACS Synth Biol. 2012 Dec 28;3(12):915–928. doi: 10.1021/sb300079h

Table 1. Medeadah and Medeao-fut1 show Medea-like selfish genetic behavior.

Progeny of crosses between parents of several different genotypes are shown. M refers to the Medeadah- or Medeao-fut1-bearing chromosome; + refers to the non–Medea-bearing homolog. The maternal copy number (0 to 2) of bcd-driven miRNAs (maternal toxin) targeting the endogenous dah or o-fut1, and the zygote copy number (0 to 2), and percentage of embryos inheriting bnk-driven dah or o-fut1 (zygotic antidote) are indicated, as are the adult progeny genotypes predicted for Mendelian inheritance of Medeadah or Medeao-fut1. The percent embryo survival was normalized to that of wild-type (w1118), which was 93.80±3.19. −, not measured.

Inherited by the
Parental Genotype Oocyte Embryo Adult M progeny % Embryo Survival %
Male Female Maternal Toxin Zygotic Antidote % Predicted Observed (dah, o-fut1) Predicted Observed (dah, o-fut1) ± sd
M/+ +/+ 0 50(0); 50(1) 50 50 (n>12,000), 50 (n>11,000) 100 98.05±2.3, 96.28±2.8
M/M M/M 2 100(2) 100 - 100 98.97±6.0, 92.74±6.0
+/+ M/+ 1 50(0); 50(1) 50 100 (n>10,000), 100 (n>12,000) 50 49.56±0.5, 47.43±2.0
M/M M/+ 1 50(1); 50(2) 100 - 100 98.05±2.3, 97.35±2.0
M/+ M/+ 1 25(0); 50(1); 25(2) 75 - 75 73.62±1.5, 73.9±1.7
M/+ M/M 2 50(1); 50(2) 100 - 100 97.7±1.0, 98.41±1.5
+/+ M/M 2 100(1) 100 - 100 99.47±1.5, 94.51±2.0
M/M +/+ 0 100(1) 100 - 100 95.22±1.1, 96.99±2.5
+/+ +/+ 0 100(0) 0 - 100 93.80±3.19