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. 2013 Aug 13;8(8):e71113. doi: 10.1371/journal.pone.0071113

Figure 5. Teratoma development in Nanos3 heterozygous mice in 129S2/Sv genetic background.

Figure 5

(A) Percentage of total tumor incidence in Nanos3 heterozygous 129S2/Sv male mice. 45% (n = 20) showed testicular tumors. Red bar: bilateral cases (5%); blue bar: unilateral cases (40%). Testes of control (wt) and Nanos3 heterozygous (cre/+) mice (inset in A). (B–D) HE-staining of testicular teratomas of 4–8 month old mice. Tumors show tissues of all three germ layers: muscle (B), squamous epithelium (C) and respiratory epithelium (D). Scale bars: 50 µm.