Table 3. Hub regions of the human brain anatomical networks derived from both the conventional DTI (C-DTI) and FLAIR-DTI (F-DTI) datasets.
Regions Location | Hubs | bi | Identified as a hub in previous studies | ||||
C-DTI | F-DTI | C-DTI | F-DTI | Anatomical networks | Functional networks | ||
CAL.L | Primary | N | Y | – | 3.133 | 3,9 | 1 |
HIP.R | Subcortical | N | Y | – | 2.004 | – | – |
IFGtriang.L | Association | N | Y | – | 2.254 | 2,11 | 1 |
IFGtriang.Ra | Association | Y | Y | 2.041 | 2.598 | 2,8 | 1 |
ITG.La | Association | Y | Y | 2.095 | 2.818 | 9,10 | 1 |
LING.L | Association | N | Y | – | 2.836 | 1,10 | |
LING.Ra | Association | Y | Y | 2.114 | 2.814 | 9 | 1 |
MOG.La | Association | Y | Y | 2.574 | 2.670 | 4,5,7,8,9,11 | 1,10 |
MTG.La | Association | Y | Y | 2.434 | 2.865 | 2,11 | 1 |
MTG.Rb | Association | Y | N | 1.970 | – | 3,9,11 | 1,10 |
PCUN.La | Association | Y | Y | 3.926 | 4.183 | 3,4,5,7,8,9 | 1 |
PCUN.Ra | Association | Y | Y | 4.095 | 2.981 | 3,4,5,7,8,9 | 1 |
PoCG.Rb | Primary | Y | N | 2.178 | – | 2,7 | 1 |
PUT.R | Subcortical | N | Y | – | 2.027 | 4,6,7,8 | – |
SFGdor.La | Association | Y | Y | 2.547 | 2.622 | 2,3, 4,5,7,9,11 | 1,10 |
SFGdor.Ra | Association | Y | Y | 2.806 | 2.477 | 2,3,4,5,7,8,9,11 | 1,6,10 |
SOG.R | Association | N | Y | – | 2.163 | 2,5,6,8 | 1 |
SPG.Lb | Association | Y | N | 1.896 | – | 4 | 1 |
SPG.Ra | Association | Y | Y | 2.509 | 2.196 | 4,6,7,8 | 1 |
1. Achard et al 2006.
2. He et al 2007.
3. Hagmann et al 2008.
4. Iturria-Medina et al 2008.
5. Gong et al 2009.
6. He et al 2009.
7. Li et al 2009.
8. Shu et al 2009.
9. Yan et al 2010.
10. Tian et al 2011.
11. Chen et al 2008.
Note: aThe hub regions shared by the networks derived from both types of DTI datasets. bThe hub regions detected only from the conventional DTI datasets. The remaining six regions are the hubs detected only from the FLAIR-DTI datasets. The symbol “–” stands for “not reported” in these previous studies. “Y” indicates that the region has been identified as a “hub”, and “N” indicates that it has not been identified as a hub.