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Association between the methylation status and mRNA expression downregulation of Apaf-1 and DAPK.
| Gene | mRNA decrease (n) | mRNA normal (n) | χ2 | P-value |
|---|---|---|---|---|
| Apaf-1 | ||||
| Methylated | 46 | 0 | 13.658 | P<0.01 |
| Unmethylated | 5 | 2 | ||
| DAPK | ||||
| Methylated | 38 | 0 | 8.256 | P<0.01 |
| Unmethylated | 12 | 3 |
Apaf-1, apoptosis protease activating factor-1; DAPK, death-associated protein kinase.
