Skip to main content
. 2013 Jun 3;4(5):751–760. doi: 10.18632/oncotarget.1044

Figure 5. Human pancreatic cancer lines grown in nude mice were analyzed with the Human Apoptosis RT Profiler PCR Array as described in the Materials and Methods.

Figure 5

The vertical bars show fold changes in gene expression compared to control. *= P<0.05 vs control. (A) Pro-apoptotic genes: TRAF3: TNF receptor-associated factor 3; TRADD: TNFRSF1A-assiciated via death domain; TP73: Tumor protein p73; TP53BP2: Tumor protein p53 binding protein 2; TP53: Tumor protein p53; TNFSF8, 10: Tumor necrosis factor superfamily, member 8, 10; TNFRSF10, 9 25, 21, 1A, 10A, 10B: Tumor necrosis factor receptor superfamily, member 10, 9, 25, 21, 1A, 10A, 10B; TNF: Tumor necrosis factor; RIPK2: Receptor-interacting serine-threonine kinase 2; PYCARD: PYD and CARD domain containing; NOD1: Nucleotide-binding oligomerization domain containing 1; NFKB1: Nuclear factor of kappa light polypeptide gene enhancer in B cells 1; LTBR: Lymphotoxin beta receptor; LTA: Lymphotoxin alpha; HRK: Harakiri, BCL2 interacting protein; GADD45A: Growth arrest and DNA-damage-inducible, alpha; FASLG: Fas ligand; FAS: Fas (TNF receptor superfamily, member 6); FADD: Fas-associated via death domain; DIABLO: Diablo, IAP-binding mitochondrial protein; DFFA: DNA fragmentation factor; DAPK1: Death-associated protein kinase 1; CYCS: Cytochrome c, somatic; CRADD: CASP2 and RIPK1 domain containing adaptor with death domain; CIDEB, A: Cell death-inducing DFFA-like effector b, a; CD70, 40, 27: CD70, 40, 27 molecule; CASP: Caspase, apoptosis-related cystine peptidase; BRAF: V-raf murine sarcoma viral oncogene homolog B1; BNIP3L: BCL2, adenovirus E1B 19kDa interacting protein 3-like; BIK: BCL2-interacting killer; BID: BH3 interacting domain death agonist; BCL2L11: BCL2-like 11; BCL10: B-cell CLL/lymphoma 10; BAX: BCL2-associated X protein; BAK1: BCL2-antagonist/killer 1; BAD: BCL2-associated agonist of cell death; APAF1: Apoptotic peptidase activating factor 1; ABL1: C-abl oncogene 1. (B) XIAP: X-linked inhibitor of apoptosis; TRAF2: TNF receptor associated factor 2; TNFRSF1B, 11B: Tumor necrosis factor receptor superfamily member 1B, 11B; NOL3: Nucleolar protein 3; NAIP: NLR family, apoptosis inhibitory protein; MCL1: Myeloid cell leukemia sequence 1; IL10: Interleukin 10; IGF1R: Insulin-like growth factor 1 receptor; CFLAR: CASP8 and FADD-like apoptosis regulator; CD40LG: CD40 ligand; BNIP2: BCL2/adenovirus E1B 19kDa interacting protein 2; BIRC6, 5, 3, 2: Baculoviral IAP repeat containing 6, 5, 3, 2; BFAR: Bifunctional apoptosis regulator; BCL2L2, 10, 1, A1: BCL2-like…; BCL2: B-cell CLL/lymphoma 2; BAG3, 1: BCL2-associated athanogene 3, 1; AKT1: V-akt murine thymoma viral oncogene homolog 1; AIFM1: Apoptosis-inducing factor, mitochondrium-associated, 1.