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. 2013 May 8;305(3):F265–F276. doi: 10.1152/ajprenal.00043.2013

Table 3.

Systemic levels of inflammatory markers in sham or RAS pigs with or without ObM (n = 7 each)

Sham
RAS
P Value for Two-Way ANOVA
Lean ObM Lean ObM Diet RAS DietxRAS
MCP-1, ng/ml 0.09 ± 0.01 0.09 ± 0.02 0.2 ± 0.07* 0.2 ± 0.04* 0.94 0.006 0.92
TNF-α, ng/ml 0.03 ± 0.08 0.06 ± 0.00 0.16 ± 0.05* 0.11 ± 0.03* 0.60 0.009 0.16
sE-selectin, ng/ml 6.7 ± 3.7 4.8 ± 4.8 15.4 ± 7.1 36.8 ± 10.8* 0.21 0.007 0.10
IFN-γ, ng/ml 0.14 ± 0.00 0.15 ± 0.02 0.55 ± 0.14* 0.40 ± 0.11* 0.45 0.001 0.35
IL-17, pg/ml 18.81 ± 1.80 26.82 ± 7.47 41.49 ± 27.76 66.50 ± 36.91 0.48 0.18 0.71
IL-10, pg/ml 8.12 ± 2.81 6.00 ± 1.34 4.85 ± 1.60 3.71 ± 0.92 0.36 0.14 0.78

Values are means ± SE. MCP-1, monocyte chemotactic protein-1; sE-selectin, soluble E-selectin.

*

P ≤ 0.05 vs. Lean-sham.

P ≤ 0.05 vs. ObM-sham.