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Mitochondria-targeted HO-1 prevents apoptosis in HO-1-deficient cells. HO-1-deficient proximal tubular epithelial cells were transiently transfected with Mito-HO-1 plasmid. A: Western blot analysis to confirm the expression of targeted HO-1. B: Western blot analysis of cleaved caspase 3 expression in control and transfected HO-1-deficient cells following hypoxia.
