Fig. 1.

Treatment with endoplasmic reticulum (ER) stress inhibitors tauroursodeoxycholic acid (TUDCA) or 4-phenlybutyric acid (PBA) can normalize ER stress marker expression in the aorta from spontaneously hypertensive rats (SHR). Top, representative Western blot images of GRP78 (A), protein disulfide isomerase (PDI; B), or C/EBP homologous protein (CHOP; C) and β-actin. Bottom, corresponding graphs showing the relative expression measured using densitometry analysis with values normalized to β-actin. Data are means ± SE (n = 6). *P < 0.05 vs. control Wistar-Kyoto (WKY) rats. Veh, vehicle.