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Treatment with ER stress inhibitors TUDCA or PBA attenuated proapoptotic marker expression and restored antiapoptotic marker expression in the aorta of the SHR. Top, representative Western blot images of BAX (A) or BCL-2 (B) and β-actin. Bottom, corresponding graphs showing the relative expression measured using densitometry analysis with values normalized to β-actin. Data are means ± SE (n = 5–8). *P < 0.05 vs. control WKY rats.
