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Stimulation of LMP1 expression and LCL proliferation by mutant EBNA2 proteins
| Mutation | Proliferationa | LMP1 transactivationb |
|---|---|---|
| Δ3-30 | − | − |
| Δ3-52 | − | − |
| Δ3-97 | − | − |
| Δ3-103 | − | − |
| Δ3-115 | NSc | NSc |
| Δ3-156 | NSc | NSc |
| Wild type | ++ | ++ |
| Δ59-103 (ΔPPR)d | ++ | ++++++ |
As determined by the transcomplementation assay.
As determined by transient-cotransfection assays in DG75 and Eli-BL cells.
NS, data not shown.
From reference 14.
