Figure 1.

Microinjection of MT-II into the DMV attenuates phasic intragastric activity. A, Representative recording showing the effects of l-glutamate and MT-II injections into the DMV on intragastric pressure (n = 12). B, Photomicrograph of a representative pipette track (arrow) and its location within the DMV (dashed lines). (Note that the track extends past the DMV, which occurred during initial entrance, but was pulled back up to allow it to reside within the DMV during microinjection of l-glutamate or MT-II). C, A representative tracing showing the effects of a higher dose of MT-II on gastric activity, subsequent to the injection of l-glutamate into the DMV. D, A camera lucida drawing depicting unilateral microinjection sites for saline vehicle (white dots), 50 pmol of MT-II (gray dots; n = 5), and 20 pmol of MT-II (black dots; each dot represents 6 sites; n = 12) into the DMV and 20 pmol of MT-II in the hypoglossal nucleus (open square; n = 3). XII, Hypoglossal nucleus; AP, area postrema; CC, central canal; TS, solitary tract.