Table 2.
Summary of functional analyses of 8×Ala replacement mutations
| Replaced residues | SARM−/− rescue |
|---|---|
| 410-417A (SAM1) | − |
| 445-452A (SAM1) | − |
| 481-488A (SAM2) | − |
| 517-524A (SAM2) | + |
| 625-632A (TIR) | − |
| 661-668A (TIR) | − |
| 697-704A (TIR) | − |
| 715-721A (post-TIR) | + |
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