Fig. 2.

Peak hyperemic (ΔFBF; A) and peak vasodilator (ΔFVC; B) responses to single-muscle contractions at 10, 20, and 40% MVC during saline (control) and l-NMMA administration in young and older adults. Under control conditions, peak hyperemic and vasodilator responses were attenuated in older adults at all contraction intensities. NO synthase inhibition (l-NMMA) blunted the peak hyperemic and vasodilator responses at all contraction intensities in young adults and at 10 and 20% MVC in older adults. *P < 0.05 vs. young. †P < 0.01 vs. control.