Table 2.
Demographic and peri-operative data, comparison between two laparoscopic phases and “open” group
| “Laparoscopy” group | “Open” group (26 patients) | p value | ||||
|---|---|---|---|---|---|---|
| Phase 1 (9 patients) | Phase 2 (11 patients) | Phase 1 versus phase 2 | Phase 1 versus “open” group | Phase 2 versus “open” group | ||
| Age (mean ± SD, years) | 41.22 ± 6.7 | 54.7 ± 11.7 | 54.7 ± 9.9 | 0.007 | 0.001 | 0.9 |
| BMI (mean ± SD, kg/m2) | 22.5 ± 2.5 | 27.1 ± 5.5 | 26.1 ± 7.6 | 0.03 | 0.01 | 0.85 |
| Previous operations | 1 (appendectomy) | 2 (1 appendectomy, 1 cholecystectomy) | 3 (1 appendectomy, 2 cholecystectomy) | – | – | – |
| Conversion | 2 (22.2 %) intra-operative complications | 1 (9 %) unexpected findings | – | – | – | – |
| Intra-operation complications | 2 (22.2 %) grade IIIb | 1 (9 %) grade I | 1 (3.8 %) grade IIIb | |||
| Number of harvested PEL nodes (mean ± SD) | 17.3 ± 7.7 | 22.5 ± 7.2 | 30.2 ± 15.8 | 0.14 | 0.02 | 0.13 |
| Number of harvested PAS nodes (mean ± SD) | – | 2 ± 1.3 (7 patients) | 5.2 ± 3.1 (7 patients) | – | – | 0.04 |
| Number of total harvested lymph nodes (mean ± SD) | 17.3 ± 7.7 | 24.4 ± 5.5 | 31 ± 16.6 | 0.04 | 0.03 | 0.2 |
| Blood loss (cc) | 222.2 ± 148.7 | 79.55 ± 15.6 | 249 ± 79.2 | 0.005 | 0.52 | 0.001 |
| Delta Hb | 2.3 ± 0.4 | 1.7 ± 0.6 | 2.7 ± 0.8 | 0.02 | 0.17 | 0.001 |
| Post-operation complicationsa | 2 grade I 1 grade IIIb (1 vaginal cuff hematoma) | 2grade I 1 grade IIIb (wound colloid) | 7 grade I 3 grade IIIb (1 wound hematoma, 2 wound dehiscence) | – | – | – |
| Operation time (min) | 397.7 ± 63.5 | 300.6 ± 19.4 | 228.7 ± 61.5 | <0.0001 | <0.0001 | 0.001 |
| Hospital stay (days) | 14.8 ± 6.9 | 9.6 ± 4.0 | 13.4 ± 4.2 | 0.05 | 0.5 | 0.01 |
PEL pelvic lymphadenectomy, PAS para-aortal lymph node sampling
aAccording to Dindo-Clavien classification