FIG. 3.
Effect of dominant-negative p53 and hTERT on cellular DNA synthesis. At 2 days after infection with the E2 virus or mock infection, HeLa/LXSN-1, HeLa/LXSN-p53CTF-3, HeLa/16E7-3, HeLa/16E7-RVY-3, HeLa/16E6-16E7-1 cells, as well as two HeLa/16E7-p53CTF cell lines and two HeLa/16E7-TERT cell lines, were assayed in quadruplicate for incorporation of [3H]thymidine. For each cell line, the data are displayed as the percentage of [3H]thymidine incorporation by the infected cells compared to mock-infected cells. The results of a representative experiment are shown in which the average of replicate samples are shown with error bars representing one standard deviation of the mean. Similar results were obtained in multiple independent experiments.