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Effect of dominant-negative p53 expression on apoptosis. At 6 days after infection with the E2 virus (bottom panels) or mock infection (top panels), HeLa/LXSN-1, HeLa/16E7-3 and HeLa/16E7-p53CTF-7 cells were assayed by flow cytometry for annexin V binding and propidium iodide uptake. The percentages of cells in the proliferating-senescing quadrant (lower left) and the apoptotic quadrant (lower right) are shown.
