Table 1.
Q, %control | D37, %control | Peak, %control | n | |
---|---|---|---|---|
EGTA-AM | 33.6 ± 6.7‡ | 57.3 ± 5.8‡ | 58.2 ± 8.1† | 7 |
BAPTA-AM | 31.6 ± 5.2‡ | 50.5 ± 4.0‡ | 53.5 ± 8.3‡ | 11 |
Nifedipine | 42.0 ± 7.3‡ | 74.3 ± 8.6* | 47.8 ± 6.9‡ | 10 |
Cd2+ | 4.4 ± 3.2‡ | 6 | ||
ω-Conotoxin | 71.7 ± 7.8* | 101.5 ± 6.7 | 62.6 ± 5.2† | 5 |
ω-Conotoxin + nifedipine | 14.7 ± 1.9‡ | 51.5 ± 3.2† | 34.2 ± 9.3* | 4 |
Ryanodine | 36.8 ± 8.6‡ | 38.8 ± 6.8‡ | 54.0 ± 8.9† | 6 |
Nifedipine + ryanodine | 12.5 ± 5.1† | 14.0 ± 6.7† | 53.7 ± 12.2 | 3 |
Data are average values of charge transfer (Q), decay to 37% of peak (D37), and peak amplitude for GABAC receptor (GABACR)-mediated evoked inhibitory postsynaptic currents (eIPSCs), normalized to GABACR eIPSC control.
P < 0.05;
P < 0.01;
P < 0.001 compared with control.