Table 3.
Predicted optimal dosage regimens of LFV/ritonavir when rifampicin is coadministered based on simulations using the final combined model
| LPV:ritonavir =4:1 |
LPV:ritonavir =1:1 12-hourly LPV dose, mg/kg |
||
|---|---|---|---|
| Body weight, kg | 12-hourly LPV dose, mg/kg | 8-hourly LPV dose, mg/kg | |
| 3.0–5.9 | 52 | 27 | 22 |
| 6.0–9.9 | 40 | 21 | 16 |
| 10.0–13.9 | 35 | 20 | 14 |
| 14.0–19.9 | 30 | 18 | 12 |
LPV, lopinavir.