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. Author manuscript; available in PMC: 2013 Aug 14.
Published in final edited form as: Hypertension. 2012 Sep 4;60(4):981–990. doi: 10.1161/HYPERTENSIONAHA.112.201509

Figure 7. PI3K inhibitor (NVP-BEZ235) supressed NCC phosphorylation by acute insulin administration.

Figure 7

A. Representative immunoblots of renal Akt, OSR1/SPAK and NCC phosphorylation in insulin-injected mice with or without administration of a PI3K inhibitor (NVP-BEZ235).

B. Densitometry analysis; NVP-BEZ235 inhibited acute insulin-induced phosphorylation of OSR1/SPAK and NCC. Mean ± SEM. (n=4). *p<0.05, **p<0.01.