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. 2004 Mar 2;101(11):3780–3785. doi: 10.1073/pnas.0400181101

Fig. 5.

Fig. 5.

Proposed scheme for activation of 1-cysPrx by interaction with πGST. Heterodimer formation of πGST with the oxidized enzyme leads to Cys-47 glutathionylation, followed by spontaneous reduction of the enzyme with GSH.