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Representation of protein structures by their distance matrices and representative local structure feature patterns (medoid submatrices). The procedure is illustrated by using 3D protein structures, distance matrices, and 50 representative patterns (medoids) of four proteins sampled one each from all-α, all-β, α/β, and α + β classes. Among the patterns, “null feature patterns” (with no Cα-Cα distance <20 Å, light pink background only) are the most abundant in all proteins.
