Table 1.
General Baseline Characteristics
| Characteristic | Both Groups (n=22) | Varenicline Group (n=11) | Placebo Group (n=11) | P Value |
|---|---|---|---|---|
| Male sex, No. | 16 | 9 | 7 | |
| Race, No. | ||||
| African American | 7 | 5 | 2 | |
| European American | 14 | 5 | 9 | |
| Mixed | 1 | 1 | 0 | |
| Handedness,a No. | ||||
| Right | 18 | 9 | 9 | |
| Left | 3 | 2 | 1 | |
| Both | 1 | 0 | 1 | |
| Age, mean (SEM), y | 36.1 (2.2) | 37.9 (3.4) | 34.4 (2.9) | .44 |
| Education, mean (SEM), y | 14.2 (0.4) | 14.4 (0.6) | 14.1 (0.6) | .74 |
| Cigarettes smoked per day, mean (SEM) [range], No. | ||||
| At start of study | 17.5 (1.6) [6–30] | 19.1 (2.4) [6–30] | 15.8 (2.0) [9–20] | .31 |
| At end of study | 11.9 (1.6) [1–30] | 11.8 (2.6) [2–30] | 12.0 (2.0) [1–24] | .96 |
| Pack yearsb | 12.6 (2.1) | 16.4 (3.5) | 8.7 (1.9) | .07 |
| FTND score | 4.7 (0.4) | 5.1 (0.7) | 4.3 (0.3) | .31 |
| Desire to quit,c % | 86.3 | 85.5 | 87.2 | .84 |
Abbreviation: FTND, Fagerstrom Test for Nicotine Dependence.
a
As assessed by the Edinburgh Handedness Inventory.
b
Calculated as the number of cigarettes smoked per day divided by number of cigarettes in a pack multiplied by the number of years smoking.
c
Assessed by asking subjects to rate their agreement with the phrase “I want to quit smoking.” Scores ranged from 0 to 100, where 0 indicates strongly disagree and 100 indicates strongly agree.