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Electropherograms of the two novel missense mutations found in PGRN (A) and in PSEN2 (B) in two of the hexanucleotide repeat carriers, respectively individuals FTD-158 (A) and FTD-223 (B). Both missense mutations have not been previously reported. After in silico analysis using Polyphen 2 software, both mutations have been predicted to be probably damaging.
