Table 1.
Samples IDs with corresponding diagnosis, number of hexanucleotide expansion and a brief family history of neurological disorders for each patient. Diagnoses are described following Rascovsky et al., 2011.
| Patient ID |
Diagnosis | Hexanucleotide Repeats # |
Family history of neurological disorders |
|---|---|---|---|
| 158 | Probable bv- FTD |
> 50 | Father - AD; Brother - MS |
| 198 | Probable bv- FTD |
> 45 | Brother - TIA; Brother - alcoholism; Daughter - migraines; Paternal aunt - dementia |
| 211 | FTD-ALS | > 50 | Mother - ALS; Brother - alcoholism; Father - dementia; Brother/Son - depression; Daughter - migraines, depression; Son - anoxic at birth |
| 223 | FTD-ALS | > 50 | Mother - dementia; Father - dementia ; Sister - FTD ; Brother - alcoholism ; Son - depression, drug use |
| 81 | Probable bv- FTD |
1 | Father - died of dementia at 77 |
| 83 | AD | 7 | Paternal grandfather - dementia |
| 85 | FTD-PPA | 7 | Father -vasc. dementia died at 68 |
| 88 | FTD-PPA | 14 | Sister - PD |
| 89 | Probable bv- FTD |
8 | Mother - LOAD; Paternal grandmother - dementia died at 89 |
| 90 | Probable bv- FTD |
4 | Father - CVA; Nephew - OCD |
| 95 | SD | 4 | Maternal aunt - dementia |
| 96 | Probable bv- FTD |
~ 25 | Father - AD onset 58; Maternal uncle - schizophrenia |
| 97 | FTD-PPA | 3 | Son - schizophrenia |
| 98 | Possible FTLD |
15 | Sister CVA. O/w no +FH |
| 99 | Probable bv- FTD |
10 | Father - PD died at 85; Mother dementia, brain tumor; 3 aunts - dementia; Maternal grandmother - dementia |
| 101 | Probable bv- FTD |
3 | Son - schizophrenia, drug abuse; Daughter - schizophrenia; Sister &Brrother - drug abuse |
| 103 | SD | 5 | Maternal grandmother - CVA; Maternal aunt - CVA |
| 107 | Probable bv- FTD |
1 | Paternal uncle - unknown mental illness |
| 111 | Possible FTLD |
2 | Sister - Korsakoff syndrome; Mother - OCD, depression; Sister -alcoholism; Twin brother - alcoholism |
| 114 | FTD-PPA | 2 | Father - AD, PD died at 63; 2 brothers - schizophrenia |
| 115 | Probable bv- FTD |
6 | Father - dementia onset at 72 paternal grandmother Parkinson’s and memory problem died in her 70”s |
| 118 | Probable bv- FTD |
6 | Father - AD; Mother - AD, depression both died in their early 90’s |
| 123 | Probable bv- FTD |
8 | Brother - learning disabilities, alcoholism; Sister - eating disorder, depression |
| 124 | Probable bv- FTD |
7 | Father - PD; aunt AD died at 79 |
| 127 | MSA | 1 | Mother - AD; Brother - CVA; Brother - brain cancer |
| 128 | Probable bv- FTD |
3 | Father - OCD; Mother - Mental disorder NOS |
| 134 | FTD-MND | 1 | |
| 136 | Probable bv- FTD |
2 | Mother - dementia at 87; maternal uncle dementia |
| 139 | FTD-PPA | 10 | Mother - depression, alcoholism |
| 143 | Probable bv- FTD |
17 | Daughter - OCD, depression |
| 144 | Probable bv- FTD |
5 | |
| 163 | FTD-MND | 9 | Paternal uncle - dementia, alcoholism |
| 176 | FTD-PPA | 2 | Mother - depression; Daughter - ADD |
| 177 | AD | 3 | Mother - LOAD; Father - alcoholism; Son - alcoholism |
| 183 | Possible FTLD |
2 | Father PTSD & depression; mother DLB, mutism; mat grandfather PD & stroke; maternal uncle DLB; 2 paternal aunts with MND |
| 194 | Probable bv- FTD |
3 | Sister - dementia; Father - stroke; Mother - depression ; Son - depression/anxiety |
| 195 | Probable bv- FTD |
6 | Mother - action tremor; Paternal grandmother - dementia; maternal great grandmother dementia |
| 199 | Possible FTLD |
2 | Father - dementia ; Daughter - seizures ; Maternal grandmother - dementia |
| 200 | Probable bv- FTD |
6 | Daughter - ADD, anxiety; Son - substance abuse |
| 201 | Possible FTLD |
4 | Father- dementia in his 60’s, stroke; Sister - dementia; Brother - stroke; Brother - epilespy, stroke; Son - epilepsy, mental illness, grandfather dementia in his 60’s |
| 203 | Probable bv- FTD |
3 | Paternal grandmother - late onset dementia at 91; Mother - MS; maternal grandmother Parkinson’s onset at 78, maternal great aunt and uncle late onset AD |
| 205 | Possible FTLD |
10 | 2 Sisters - anxiety; Sister - PSP; Daughter - eating disorder; Daughter - anxiety, depression; Daughter - schizophrenia; Son/2 Daughters - depression |
| 207 | Possible FTLD |
7 | Siblings tremor, anxiety, alcoholism, substance abuse, mother died at 83 had dementia and anxiety; father died at 79 had Parkinson’s and anxiety. |
| 209 | Probable bv- FTD |
7 | Father - stroke ; Brother - born w/hole in skull; Daughter - seizure disorder |
| 210 | Possible FTLD |
7 | Maternal grandfather - dementia |
| 212 | Probable bv- FTD |
5 | |
| 215 | Possible FTLD |
2 | Mother - AD ; Father - dementia ; Brother - depression ; Son - arthrogyrosis |
| 216 | Possible FTLD |
9 | Sister - mild stroke, depression |
| 217 | Probable bv- FTD |
2 | father died at age 82 no dementia but paternal grandfather died of dementia at 81 |
| 218 | Probable bv- FTD |
~ 25 | Mother - dementia; Son - ALS; Maternal aunt - AD |
| 219 | Probable bv- FTD |
2 | Daughter - anx, dep, neurocardiogenic syndrome ; Brothers - depression ; Sister - anx, dep, ADHD ; Father - dementia ; Mother - stroke |
| 221 | Probable bv- FTD |
10 | Father - vascular dementia at 78 |
| 222 | Possible FTLD |
2 | Father - AD, PD, heart disease; Brother - alcohol abuse |