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. 2013 Jul 31;143(9):1509–1519. doi: 10.3945/jn.113.174599

FIGURE 5.

FIGURE 5

Dynamic changes of tryptophan and tryptophan metabolites after simulation of tryptophan input due to meals in a period of 24 h. The tryptophan inputs were simulated by delivering one-fourth of the daily dose of tryptophan between 0700 and 0800 h, one-fourth of the daily dose of tryptophan between 1200 and 1300 h, and one-half of the daily dose of tryptophan from 1800 to 1900 h. The word “out” denotes urinary metabolites. AA, anthranilic acid; bptrp, tryptophan in peripheral circulation; gut, tryptophan in gut; HaA, 3-hydroxyanthranilic acid; HK, 3-hydroxykynurenine; hptrp, tryptophan in portal circulation; KA, kynurenic acid; Kyn, kynurenine; Ltrp, tryptophan in liver; Mtrp, tryptophan in muscle; QA, quinolinic acid; XA, xanthurenic acid.