Table 3.

Relative risks of incident type 2 diabetes according to psoriasis among younger (<60 years during the follow-up) US women and men ¹

Study	Diabetes cases	Person-years	Age-adjusted RR (95% CI)	Multivariate RR 2 (95% CI)
NHS
No psoriasis	733	165,508	1.00	1.00
Psoriasis	23	2,982	1.73 (1.14–2.62)	1.35 (0.89–2.05)
HPFS
No psoriasis	622	245,644	1.00	1.00
Psoriasis	23	6,610	1.30 (0.86–1.97)	1.20 (0.79–1.82)
NHS/NHSII
No psoriasis	4,568	1,636,217	1.00	1.00
Psoriasis	156	29,141	1.76 (1.50–2.06)	1.26 (1.08–1.48)
NHS/NHSII/HPFS
No psoriasis	5,190	1,881,861	1.00	1.00
Psoriasis	179	35,751	1.69 (1.46–1.96)	1.26 (1.08–1.46)

Abbreviations: CI, confidence interval; RR, relative risk.

¹NHS II data not shown because study participants were all <60y during the follow-up, the same as table 2.

²Simultaneously adjusted for age, body mass index (<21.0, 21.0–22.9, 23.0–24.9, 25.0–26.9, 27.0–29.9, 30.0–32.9, 33.0–34.9, 35.0–39.9 or ≥40.0 kg/m²), smoking (never, past, current with 1–14, 15–24 or ≥25 cigarettes/day), alcohol intake (no, <4.9, 5.0–14.9 or ≥15.0 g/d), physical activity (<3.0, 3.0–8.9, 9.0–17.9, 18.0–26.9 or ≥27.0 metabolic equivalent hours/wk), race (Caucasian, Asian, Hispanic or African American), family history of diabetes (yes or no), hypertension (yes or no), hypercholesterolemia (yes or no), current aspirin use (yes or no), multi-vitamin use (yes or no), postmenopausal hormone use (for women only, premenopause, never, current or past users).