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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Biotechnol J. 2013 Apr;8(4):434–447. doi: 10.1002/biot.201200199

Figure 2.

Figure 2

Functionality of hPSC derivatives. Synthetic-vSMCs and contractile-vSMCs derived from hPSCs, transplanted subcutaneously, were shown to: (A) migrate to the host vasculature and locate in the outer layers of the mouse blood vessels that penetrated into the Matrigel plug. (B) On some occasions, the human contractile vSMCs were found to wrap the smaller mouse vasculature circumferentially. Human cells in red, mouse vasculature in green, and nuclei in blue. Some human cells are indicated with white arrows. For details about method please refer to ref. [75].