Efficacy of peptides in animal models.
A, effect of peptides Ugr 9-1, Ugr 9-2, and Ugr 9-3 on the mice withdrawal latency on a hot plate in the thermal hyperalgesia test after CFA injection (n = 7). B, the attenuated response of Ugr 9-1-treated mice to intraperitoneal administration of acetic acid estimated by the number of writhes in 15-min intervals (n = 7). C, Ugr 9-1, Ugr9-2, and Ugr 9-3 at 0.5 mg/kg (n = 10) did not significantly alter time spent on the rota-rod. Results presented as mean ± S.E.; **, p < 0.005; *, p < 0.05.