FIGURE 3.

Kv2.2 mRNA expression is reduced by chronic exposure to elevated fatty acids. 832/13 cells were cultured for a total of 3 days and exposed to a mixture of 1 mm O/P complexed to BSA in a 2:1 ratio or to BSA alone for the final 24 or 48 h as indicated. qRT-PCR measurement of Kv2.1 expression (A) and Kv2.2 expression (B) is shown. C, GSIS analysis. Data for all panels represent six independent experiments, each performed in duplicate. *, p < 0.001; #, p < 0.01; @, p < 0.05. Error bars represent S.E. uU, microunits.