Figure 1.
Twenty-eight-day mortality according to stratification of vancomycin trough concentrations and AUC values. Data were presented as percentages. P values were determined by χ2 tests. Stratification of vancomycin trough concentrations revealed no statistically significant relationship with 28-day mortality at any of the breakpoints evaluated (P = 0.603 [A]). However, AUC values of 250–350 μg*h/mL and 350–450 μg*h/mL were associated with significantly lower 28-day mortality than AUC values <250 and >450 μg*h/mL (P < 0.001 [B]).
Abbreviation: AUC, area under the concentration curve.