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. Author manuscript; available in PMC: 2013 Aug 14.
Published in final edited form as: Nat Struct Mol Biol. 2012 Oct 14;19(11):1168–1175. doi: 10.1038/nsmb.2400

Figure 6.

Figure 6

DR2 Alu transcripts and riRNAs regulate stem cell proliferation. (a,b) Immunostaining showed that RA treatment suppressed cell proliferation as marked by KI-67. Microinjection of synthesized riRNAs or the full-length AluSx overexpression construct similarly suppressed proliferation of Ntera2 cells. However, microinjection of AGO3 or DR2 Alu siRNAs prevented the RA-mediated proliferation arrest. Scale bar: 20 µm for the middle image in panel b; 60 µm for the rest of a, b panels. (c) Bar graphs showed the counting results from three independent injection experiments. (mean±SEM; *p<0.05, **p<0.01)