Table 2.
Example of dosing nomogram for maintenance of warfarin therapy: Recommended actions to maintain a target INR of 2.0–3.0 and 2.5–3.5.
| TARGET INR OF 2.0–3.0 | ACTION TO MAINTAIN TARGET INR | TARGET INR OF 2.5–3.5 |
|---|---|---|
| INR result | INR result | |
|
| ||
| < 1.5 | Extra dose, increase weekly dose by 10%–20% | < 2 |
| 1.5–1.9 | Increase weekly dose by 5%–10% | 2–2.4 |
| 2–3 | No change | 2.5–3.5 |
| 3.1–3.5 | Decrease weekly dose by 5%–10% | 3.6–4 |
| 3.6–4.9 | Hold 1 dose, decrease weekly dose by 10%–20% | 4.1–4.9 |
| 5–9 | Hold 2 doses, decrease weekly dose by 10%–20% | 5–9 |
| > 9 | Urgent evaluation | > 9 |
INR—international normalized ratio.
Data from University of Wisconsin-Madison Health.14