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. 2013 Aug 14;8(8):e72653. doi: 10.1371/journal.pone.0072653

Table 3. Enriched genes in the 30 top Gene Ontology (GO) terms.

Genea # terms involved Ratio of significant SNPsb Most significant SNP p-valuec
PARK2 6 28/512 rs574165 0.001
UBR3 6 2/36 rs16857407 0.020
ANAPC10 5 1/8 rs1455137 0.035
BRAP 5 1/11 rs10744774 0.019
CADM1 5 2/72 rs6589485 0.006
CARD8 5 5/23 rs10416565 0.008
CBL 5 2/13 rs2249466 0.027
CRTAM 5 2/22 rs3107606 0.009
DDB2 5 2/7 rs3781619 0.013
FBXL6 5 3/8 rs3817681 0.016
FBXO22 5 3/5 rs335675 0.011
FBXO3 5 1/28 rs831627 0.004
FBXO7 5 8/29 rs738263 0.007
GLMN 5 1/3 rs3103174 0.017
INS 5 3/9 rs11042978 0.002
MALT1 5 3/22 rs9783885 0.021
MYLIP 5 6/18 rs11969250 0.004
NLRP3 5 3/40 rs9988572 0.001
RNF217 5 2/42 rs552705 0.029
SMURF1 5 2/16 rs12672417 0.020
UBE2D2 5 2/7 rs769052 0.033
UBE2E1 5 4/20 rs12629302 0.008
UBE2H 5 1/24 rs10246707 0.024
UBE2L3 5 1/10 rs13054355 0.006
UBE2M 5 3/8 rs7249714 0.006
UBR5 5 4/27 rs10102559 0.003
UHRF2 5 1/24 rs1547258 0.030
WWP2 5 3/28 rs7200005 0.011
ZER1 5 1/4 rs10988111 0.017
APOA1 4 1/6 rs10047459 0.015
CCKBR 4 2/19 rs2880829 0.004
CIDEA 4 1/16 rs8084404 0.040
FOXP3 4 1/7 rs5906761 0.016
NLRP12 4 2/19 rs7259148 0.005
ROBO2 4 15/171 rs9836971 0.005
SLIT2 4 6/106 rs12503652 0.003
a

Genes that have at least one SNP with a p-value < 0.05 and are involved in at least 4 gene sets were listed.

b

The numerator is the number of SNPs with a p-value < 0.05 in a gene and the denominator is the total number of SNPs mapped to the gene.

c

The p-value of the most significant SNP in the gene.