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. 2013 Aug 14;8(8):e71334. doi: 10.1371/journal.pone.0071334

Table 2. A proteomic comparison was made between SVZ and HPC cultures.

Protein Gene Symbol Protein mRNA
Up in SVZ HPC/SVZ HPC/SVZ
Ras-related protein R-Ras2 RRAS2 0.40387 0.76
Collagen alpha-1(I) chain COL1A1 0.40303 0.94
Filamin-B FLNB 0.53199 1.01
Microtubule-associated protein 1B MAP1B 0.53036 1.09
Neurofilament medium polypeptide NEFM 0.25961 0.93
Collagen alpha-1(XVIII) chain COL18A1 0.27087 1.04
Filamin-C FLNC 0.55772 0.90
LIM domain only protein 7 LMO7 0.57999 1.00
Heat shock-related 70 kDa protein 2 HSPA2 0.32062 1.06
Collagen alpha-2(I) chain COL1A2 0.60116 1.00
Glycogen phosphorylase, brain form PYGB 0.63077 0.89
Eukaryotic translation initiation factor 5B EIF5B 0.69052 1.03
Up in HCP
Mas-related G-protein coupled receptor member F MRGPRF 2.0517 0.83
Phosphate carrier protein, mitochondrial MCART1 1.7571 1.04
NAD(P)H dehydrogenase [quinone] 1 NQO1 1.7365 1.13
Histone H1.2 HIST1H1C 1.7194 0.96
Fatty acid desaturase 2 FADS2 1.7104 0.90
Glucose-6-phosphate 1-dehydrogenase G6PD 1.6318 1.10
Histone H1.5 HIST1H1B 1.4966 0.99
Argininosuccinate synthase ASS1 1.4611 1.26
Collagen alpha-2(VI) chain COL6A2 1.4224 1.24
Splicing factor, arginine/serine-rich 7 SFRS7 1.3969 0.96

A proteomic comparison was made between SVZ and HPC cultures for differentially expressed proteins using ‘Silac’ technology that discriminates proteins synthesized in culture incorporating ‘heavy’ amino acids. Data were obtained for 840 proteins. Twelve of these were shown to be upregulated >1.4 fold in SVZ and 11 were shown to be upregulated >1.4 fold in HPC (p<<0.05, n = 3). Column 4 indicates whether this upregulation is reflected in the RNA microarray data (bolded ratios are those that are not).