Table 1. Profile of the blind subjects.

Subjects	Age (years)	Educational level	Onset of blindness	Diagnosis	Performance (**)
EB1	23	Some college	Birth	Persistent hyperplastic primaryvitreous involving both eyes	NA
EB2	28	High school	Birth	Genetic (*)	74 (°)
EB3	31	College degree	Birth	Leber congenital amaurosis	66
EB4	42	High school	Birth	Retinopathy of prematurity	68
EB5	57	College degree	<18 months	Bilateral retinoblastoma	73 (°)
EB6	31	College degree	Birth	Anterior chamber cleavagesyndrome (Peters syndrome)	73
EB7	43	High school	Birth	Unknown, postmature birth (*)	66
EB8	40	College degree	Birth	Premature birth	76
EB9	52	College degree	Birth	Severe retinal dystrophy (*)	72
EB10	48	High school	<24 months	Bilateral retinoblastoma	68

Note: EB: early blind; all subjects were male and right handed; (*): no additional details available.

(**) Behavioral performance in a variety of higher-level odor processing tasks (global percentage of correct answers) before fMRI (see text and Table S1 for details and scores of each task). (°) Behavioral performance in age-matched control was not available for this subject. As subjects EB5 and EB10 had very poor vision from birth and underwent a bilateral eye enucleation by the age of 18–24 months, they were considered early blind. They did not remember any visual experience.