Figure 10. Galectin-7 expression induced by p53^R175H .

mutant is inhibited by CAPE. (A) Inhibition of galectin-7 mRNA levels by CAPE in MDA-MB-453 cells transfected with the expression vector encoding p53^R175H or with the (empty) pCDNA3.1 control vector (CTRL). GAPDH was used as loading control. (B) Effect of CAPE on NF-κB reporter activity in MDA-MB-453 cells transfected with the expression vector encoding p53^R175H or with the (empty) pCDNA3.1 control vector (CTRL). Transfection efficiency was normalized by co-transfection with a β-galactosidase reporter vector.