Table 2. Gene ontologies with differentially expressed genes in response to high fat diet.
| Functional Group | Functional Subgroup | Enrichment Score* | P value** | Diet Score# | % genes in group present |
|---|---|---|---|---|---|
| Biological process | 2.54 | 0.05 | 7.80 | 36.33 | |
| Cellular process | 39.07 | 0.001 | 7.27 | 41.18 | |
| Lipid metabolic | 21.61 | 0.001 | 8.53 | 49.28 | |
| Carbohydrate metabolic | 4.21 | 0.01 | 8.77 | 42.80 | |
| Establishment of localization | 17.53 | 0.001 | 7.04 | 41.18 | |
| Transport | 12.99 | 0.001 | 6.94 | 41.28 | |
| Immune system | 9.54 | 0.001 | 7.82 | 48.16 | |
| Cell Growth | 5.21 | 0.01 | 7.33 | 46.85 | |
| Developmental | 3.86 | 0.02 | 7.17 | 38.11 | |
| Fat cell differentiation | 1.61 | 0.2 | 9.58 | 42.59 | |
| White fat cell | 0.35 | 0.7 | 9.92 | 33.33 | |
| Brown fat cell | 1.31 | 0.32 | 12.58 | 42.31 | |
| Metabolic process | 2.78 | 0.06 | 7.44 | 37.23 | |
| Cellular component | 2.37 | 0.09 | 7.03 | 36.35 | |
| Molecular component | 1.22 | 0.29 | 7.04 | 36.26 |
Listed are top functional groups of high fat diet induced genes (FDR less than <0.05). * A high value of enrichment score indicates that the functional group is over-represented in the gene list. ** P value is the - log p-value of a Chi-square test.