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. 2013 Aug 14;8(8):e72367. doi: 10.1371/journal.pone.0072367

Table 2. Gene ontologies with differentially expressed genes in response to high fat diet.

Functional Group Functional Subgroup Enrichment Score* P value** Diet Score# % genes in group present
Biological process 2.54 0.05 7.80 36.33
Cellular process 39.07 0.001 7.27 41.18
Lipid metabolic 21.61 0.001 8.53 49.28
Carbohydrate metabolic 4.21 0.01 8.77 42.80
Establishment of localization 17.53 0.001 7.04 41.18
Transport 12.99 0.001 6.94 41.28
Immune system 9.54 0.001 7.82 48.16
Cell Growth 5.21 0.01 7.33 46.85
Developmental 3.86 0.02 7.17 38.11
Fat cell differentiation 1.61 0.2 9.58 42.59
White fat cell 0.35 0.7 9.92 33.33
Brown fat cell 1.31 0.32 12.58 42.31
Metabolic process 2.78 0.06 7.44 37.23
Cellular component 2.37 0.09 7.03 36.35
Molecular component 1.22 0.29 7.04 36.26

Listed are top functional groups of high fat diet induced genes (FDR less than <0.05). * A high value of enrichment score indicates that the functional group is over-represented in the gene list. ** P value is the - log p-value of a Chi-square test.