Table 1. Pregnancy outcomes from gravid mice showing no signs of listeriosis and culture-negative intrauterine contents.
| Strain inoculated | Dose per mousea | Number of mice examined | Mice with viable fetuses | Average litter sizeb | Total number of viable fetuses | Average viable fetal weight (g) | Average viable fetal weight (g) per litterc | Number of mice with resorbed embryosd | Average resorptions per gravid mouse | Average resorptions per viable fetus |
|---|---|---|---|---|---|---|---|---|---|---|
| Sham | 0 | 5 | 5 | 14.2 ± 1.9 | 71 | 1.43 ± 0.15 | 1.43 ± 0.07 | 0 | 0 | 0 |
| F6212 | 1 x 106 | 3 | 3 | 14.0 ± 3.6 | 42 | 1.34 ± 0.08 | 1.34 ± 0.06 | 2 | 1 | 0.07 |
| F6212 | 1 x 107 | 2 | 1 | 15.0 ± (0) | 15 | 1.28 ± 0.05 | 1.29 ± (0) | 1 | 4 | 0.53 |
| F6212 | 1 x 108 | 4 | 4 | 14.5 ± 2.4 | 58 | 1.31 ± 0.12 | 1.31 ± 0.00 | 0 | 0 | 0 |
| 10403S | 1 x 107 | 5 | 4 | 13.3 ± 1.5 | 53 | 1.33 ± 0.13 | 1.34 ± 0.11 | 1 | 2.6 | 0.25 |
Average values significantly different from the sham inoculated group are in bold.
Mice were intragastrically inoculated the colony forming units (cfu) denoted, or sham inoculated with PBS at 6.5 gd as described in the text.
Only litters with viable fetuses are considered. Only viable fetuses were counted in litter size determinations. ± denotes standard deviation (SD). A parenthetical SD indicates that a single litter was examined and consequently could not be included in the statistical analysis.
Calculations were made by summing the average fetal weight per litter and diving by the number of gravid animals in each group. A parenthetical SD value indicates that a single litter was examined and consequently could not be included in the statistical analysis.
One mouse inoculated with F6212 at 1 x 107 cfu and one mouse inoculated with 10403S had only resorbed embryos, no viable ones.