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. 2013 Aug 14;8(8):e70675. doi: 10.1371/journal.pone.0070675

Figure 3. Stress-induced effect on PI3K/AKT, cAMP/PKA/CREB and GH/STAT5b signaling pathways.

Figure 3

The evaluation of the stress effect on theses pathways was conducted in nuclear and cytosolic proteins with Western blot. Histone H3 served as a loading control for nuclear proteins and β-actin for cytosolic proteins. AR: adrenergic receptor; AR-antagonists given prior to stress inhibited α1-, α2- and beta-AR signaling; prazosin (α1-AR ainhibitor), atipamezole (α2-AR inhibitor), propranolol (β-AR inhibitor).