Table 2. Associations between SNPs and risks of type 2 diabetes in Dhaka, Bangladesh, 2001–2011.
Marker | Gene | Adjusted Odds Ratioa | 95% Confidence Interval | p-valueb | q-value |
rs17070905 | ADAMTS9 | 2.30 | 1.17–4.50 | 0.015 | 0.247 |
rs17070967 | ADAMTS9 | 2.02 | 1.00–4.06 | 0.049 | 0.408 |
rs6766801 | ADAMTS9 | 2.33 | 1.18–4.60 | 0.015 | 0.247 |
Models were adjusted for age, sex, BMI, smoking, skin lesion, and arsenic in drinking water using penalized splines.
P-value for overall effects of three markers in ADAMST9 was 0.006 (q-value = 0.066) using kernel machine regression adjusting for age, sex, BMI, smoking, skin lesion, and arsenic in drinking water.