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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Biochem J. 2013 Sep 1;454(2):191–200. doi: 10.1042/BJ20130317

Figure 3. Structures of anthrapyrazolone and 4-anilinoquinazoline inhibitors bound to APH(3’)-Ia.

Figure 3

A) APH(3’)-Ia•kanamycin•SP600125 and B) APH(3’)-Ia•kanamycin•tyrphostin AG 1478 complexes. Electron density shown is simulated annealing Fo-Fc omit density at 2.5 and 2.0 σ for SP600125 and AG 1478, respectively.