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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Biochem J. 2013 Sep 1;454(2):191–200. doi: 10.1042/BJ20130317

Figure 7. C3-substituted PP compounds rescue activity of kanamycin-resistant E. coli.

Figure 7

Shown are growth curves of E. coli ΔtolC ΔbamB expressing APH(3’)-Ia grown in the presence of 1-NAPP1 alone (64 μM, light grey circles), 1-NA-PP1 (64 μM) in combination with kanamycin at ¼ MIC (black circles), 1-NM-PP1 alone (32 μM, light grey dashed line) and 1-NM-PP1 (32 μM) in combination with kanamycin at ¼ MIC (dark grey dashed line). Also shown are normal growth control (solid black line) and kanamycin at ¼ MIC only (solid grey line). Inset: corresponding ARF [24] values.