Table 1.
Baseline Participant Characteristics
| All Subjects (n=80) | |||
|---|---|---|---|
| Mean ± SD | Minimum, Maximum | ||
| Age, yr | 18.1 ± 2.7 | 13.3, 27.1 | |
| Height, cm | 164.0 ± 7.0 | 148.3, 180.1 | |
| Weight, kg | 48.6 ± 5.8 | 37.4, 67.9 | |
| BMI, kg/m2 | 18.0 ± 1.5 | 14.8, 22.9 | |
| BMI, % of median for age | 86 ± 7 | 68, 109 | |
| Fat mass, kg | 8.6 ± 2.7 | 3.7, 17.4 | |
| Lean mass, kg | 37.4 ± 4.5 | 27.2, 47.9 | |
| 25(OH)D, ng/mL | 38.3 ± 14.4 | 9, 83 | |
| PTH, pg/mL | 29.7 ± 11.2 | 10.2, 70.2 | |
| Lumbar spine: | aBMD, g/cm2 | 0.89 ± 0.10 | 0.67, 1.15 |
| Z, SD | –0.90 ± 1.00 | –3.3, 1.2 | |
| Total hip: | aBMD, g/cm2 | 0.89 ± 0.11 | 0.66, 1.19 |
| Z, SD | –0.36 ± 0.92 | –2.2, 2.0 | |
| Whole body: | aBMD, g/cm2 | 1.06 ± 0.07 | 0.92, 1.28 |
| Z, SD | 0.07 ± 0.94 | –2.0, 2.2 | |
| Median (Q1–Q3) | Minimum, Maximum | ||
|---|---|---|---|
| Duration of AN, mo | 12 (4–28) | 1, 132 | |
| Months amenorrhea† | 11 (5–20) | 1,144 | |
| N (%) | |||
| White | 71 (89) | ||
| Hispanic | 2 (3) | ||
| Lumbar spine: | Z ≤ –1 SD | 41 (51) | |
| Z ≤ –2 SD | 13 (16) | ||
| Total hip: | Z ≤ –1 SD | 19 (24) | |
| Z ≤ –2 SD | 3 (4) | ||
| Whole body: | Z ≤ –1 SD | 11 (14) | |
| Z ≤ –2 SD | 1 (1) | ||
†
Excludes five participants with primary amenorrhea; includes six participants who were on COCs at time of recruitment and discontinued use of the medication for at least 1 month before the baseline visit.