Table 1.
Study population characteristics among men of African descent from the U.S. and Jamaica.
| Characteristics | Cases | Controls | p value |
|---|---|---|---|
|
| |||
| Number of Participants, n | 279 | 535 | --- |
|
| |||
| Age at enrollment (yrs), Median (range) | 67 (45–91) | 53 (27–89) | <0.0001a |
|
| |||
| Family History of Prostate Cancer, n (%) | |||
| Yes | 35 (16.1) | 21 (12.5) | |
| No | 182 (83.9) | 147 (87.5) | 0.316b |
| Missing | 62 (22.2) | 367 (68.6) | |
|
| |||
| PSA (ng/ml), median (range) | 11.7 (0.01–10,000) | 0.9 (0.0–4.0) | <0.0001a |
|
| |||
| PSA (ng/ml)b, n (%) | |||
| < 4 | 37 (13.8) | 517 (99.8) | <0.0001b |
| ≥ 4 | 231 (86.2) | 1 (0.2) | |
| Missing | 11 (0.04) | 17 (0.03) | |
|
| |||
| Gleason Score, n (%) | |||
| 4 | 12 (5.6) | ||
| 5 | 14 (6.5) | ||
| 6 | 74 (34.2) | ||
| 7 | 70 (32.4) | ||
| 8 | 18 (8.3) | ||
| 9 | 22(10.2) | ||
| 10 | 6 (2.8) | ||
| Missing | 63 (22.6) | ||
|
| |||
| Global WAA, median (range) | 0.79 (0.25–0.94) | 0.767 (0.25–0.95) | 0.107a |
Abbreviations: PSA, prostate specific antigen; WAA, West African Ancestry;
a
Wilcoxon Sum Rank Test was used to examine whether differences exists within median age (yrs),
b
Chi-square test of heterogeneity was used to determine whether the prevalence of family history or high PSA levels (PSA 4 ng/mL) vary between cases and controls, PSA (ng/ml) and Global WAA between cases and controls.