Table 4A. Interactions and main effects of TLR-associated SNPs as predictors of prostate cancer using age-adjusted MDR.
MDR models for U.S. and Jamaican men of African descent combined.
| Best Total Population Model (dbSNPID #) | Cross Validation Consistency (CVC) | Average Testing Accuracy (ATA) | Permutation Testing p-value |
|---|---|---|---|
|
| |||
| One Factor | 10/10 | 0.5722 | 0.001 |
| TLR6 rs2381289 | |||
|
| |||
| Two Factor | 10/10 | 0.6113 | 0.001 |
| TLR10 rs11096957 | |||
| TLR6 rs2381289 | |||
|
| |||
| Three Factor | 10/10 | 0.6505 | 0.001 |
| TLR10 rs11096957 | |||
| TLR6 rs2381289 | |||
| IRF3 rs2304206 | |||